Anti CCP (Antibody to Cyclic Citrullinated Peptide) Lab Test

Rheumatoid Factor

What Is CCP?

CCP meaning is Cyclic citrullinated peptide, it is a circular peptide that contains the amino acid citrulline. Both citrullination and anti – citrullinated peptide antibodies play an important role in initiating inflammatory responses in autoimmune diseases like rheumatoid disease. 

 

What is anti – CCP Test?

The Anti- CCP Test is a blood test that can be used by doctors to confirm a diagnosis of rheumatoid arthritis . The ACCP test detects the presence of citrulline antibodies in the blood. A positive Anti- Ccp Test result could be used in conjunction with other blood tests, physical examinations and imaging tests to confirm rheumatoid arthritis diagnosis. The anti – CCP test normal range is less than 20 u/ml. A level above 20 is indicative of the possibility of Rheumatoid Arthritis.  

These anti -CCP’s are proteins produced by the immune system in response to perceived threat from citrulline. The Anti – Ccp is directed by the body against the peptides and  proteins that are citrullinated. These autoantibodies are found to be present in a large majority of people affected with Rheumatoid arthritis.

RA is a chronic systemic autoimmune disease that causes inflammation, pain, stiffness, and destructive changes in the hands, feet, and other joints throughout the body. Conversion of arginine to citrulline plays a role in the autoimmune inflammatory process seen in the joints of those with Rheumatoid arthritis (RA). 

 

When do you expect results?

24 to 36 Hours

 

Why Get Tested?

Anti-CCP test is ordered to detect rheumatoid arthritis and helps identify the type of arthritis and asses the prognosis with rheumatoid arthritis.

 

Reason to take Anti CCP (Antibody to Cyclic Citrullinated Peptide) Test

An anti CCP test can be taken by any individual who may be susceptible to rheumatoid arthritis. General symptoms that may be observed are stiff joints that lead to painful walking or even holding of any objects by hand, especially in the morning or even after the body has rested for a while. Pain in the joints and bones, fatigue and low grade fever.

 

Preparations Needed for Anti CCP (Antibody to Cyclic Citrullinated Peptide) Test

Preparatory instructions during specimen collection*:No Fasting Required.No other special preparations required.

 

Sample Required?

Specimen type:Serum (Blood Sample) Specimen collection procedure:Venipuncture - Collection of blood from a vein, usually from the arm.

 

Anti -CCP Positive Treatment

Once a person is tested for anti - CCP positive there is no natural way to reduce the anti – ccp levels in the body and the person has to seek proper Anti – Ccp Positive Treatment. The Anti – CCP Positive Treatment consists of non steroid anti – inflammation drugs. If that does not help then more stronger medicines can be prescribed by a doctor. 

 

Anti – TNFa treatment or Infliximab treatment for anti – ccp and Rheumatoid arthritis may also be used to reduce anti – ccp antibodies in patients.

 

Anti – CCP Test Cost

The Anti – CCP Test Cost is quite economical and is easily affordable. There is no fixed Anti – CCP Test Cost across India owing to several factors. Also the Anti – CCP Test price is found to vary from the traditional anti - CCP lab tests to the varied at home healthcare service providers who bunch together several lab tests and offer attractive Anti – CCP Test price, along with other tests.

 

How can we help?

Why queue in front of pathological labs or clinics to get such a simple procedure done, just give us a call and let us provide you with a highly reliable and certified Anti – CCP test at your home. Our representative phlebotomist will visit you at your home at a time and day of your convenience and collect the blood sample. Not only that we would also home deliver the anti – ccp test report to you, so you can enjoy and relax with your loved ones rather than wasting it on clinical procedures.

 

Understanding results of Anti CCP (Antibody to Cyclic Citrullinated Peptide)

Reference RangeInterpretation
Adult male75-205 ng/dL

‘*A Reference range is a set of values which helps the healthcare professional to interpret a medical test. It may vary with age, gender, and other factors. Reference ranges may also vary between labs, in value & units depending on instruments used and method of establishment of reference ranges’

References

  1. https://labtestsonline.org/tests/cyclic-citrullinated-peptide-antibody
  2. https://www.ncbi.nlm.nih.gov/pubmed/17434910
  3. https://www.nps.org.au/australian-prescriber/articles/antibodies-to-cyclic-citrullinated-peptides-how-they-assist-in-the-diagnosis-of-rheumatoid-arthritis
  4. https://www.archivesofrheumatology.org/full-text/480