Helicobacter Pylori (H. pylori) IgG antibodies Lab Test

Helicobacter Pylori (H. pylori) IgG antibodies
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What is H pylori Infection?

H pylori infection is the chronic inflammation of the stomach and the duodenum caused by the H pylori bacteria. This H pylori bacteria can stay inactive in the stomach for a long time before casing sores or ulcers.

H pylori Symptoms

The most common H pylori symptoms are;

  • Belching
  • Bloating
  • Nausea and vomiting
  • Abdominal Discomfort

Serious H pylori infection can show the following symptoms;

  • Abdominal pain
  • Nausea and Vomiting
  • Passing dark stools
  • Fatigue
  • Anemia
  • Reduced appetite
  • Diarrhoea
  • Peptic Ulcers
  • Heartburn
  • Bad Breath

How can we help?

We offer a wide range of healthcare services at home including doctor’s consultation to nurse care and lab testing. So you can depend on us for providing a complete healthcare package at your home.

We even provide Helicobacter Pylori home test, for your comfort so you don’t have to take any hassle of getting tested rather just sit back and call us. Our representative would soon be at your home to collect the test samples, not only that we would also deliver the H.Pylori test report at your home.

What is H Pylori Test?

H pylori test is used for diagnosing an infection caused by the H pylori bacteria and also to check for the effectiveness of the H pylori treatment. The various methods adopted for H pylori test are blood test, breath test and stool test.

Both breath and stool are said to be more effective in the detection of H pylori infection than a blood test. 

When do you expect results?

24 to 36 Hours

Why Get Tested?

The Helicobacter pylori tests asses infection by the bacteria. It may be done to detect reasons for gastritis or peptic ulcers and monitor treatment of the infection.

Reason to take Helicobacter Pylori (H. pylori) IgG antibodies Test

Symptoms are not mandatory in the patient but there could be possibilities of signs like 

  • Mild nausea
  • Anemia
  • Difficulty swallowing 
  • Abdominal pain
  • Bloating and fullness
  • Indigestion
  • Vomiting 
  • Hungry feeling 1 to 3 after eating
  • Gastrointestinal bleeding
  • Unexplained weight loss

Clinical Definition of Helicobacter Pylori (H. pylori) IgG antibodies

Helicobacter pylori is a spiral-shaped, gram-negative bacillus that has been associated with gastritis, gastric and duodenal ulcers, and gastric malignancies. Infection by the bacteria causes the inflammation of the stomach lining and the development of chronic duodenal, peptic and gastric ulcers, active gastritis, stomach cancer and other inflammatory gastroduodenal lesions.

Four tests may be most commonly used to detect H. pylori:

  • antibody test - To check for IgG & IgA antibodies against the bacteria.
  • Urea breath test - To detect and identify the presence of the bacteria in the stomach by checking for the urease produced by it.
  • Stomach biopsy - Tissue examination of stomach lining and small intestine
  • stool antigen test

Sample Required?

Specimen type: Serum (Blood Sample)

Specimen collection procedure: Venipuncture - Collection of blood from a vein, usually from the arm.

Specimen type: Breath Test

Specimen collection procedure: Urea labeled with uncommon isotope will be given to swallow. 10-20 minutes later, isotope labeled carbon dioxide will be detected from the exhaled breath.

H pylori Treatment

The H pylori treatment can be done with the help of antibiotics. Doctors initiate the H pylori treatment with two antibiotics simultaneously to prevent the Helicobacter pylori bacteria from forming a resistance against the antibiotic. Acid suppressing drugs can also be used to help the healing of the stomach lining. 

H Pylori Treatment Side Effects

The medication used for h pylori treatment can cause some side effects. The common H pylori treatment side effects are as follows;

  • Unpleasant after taste in the mouth
  • Headache
  • Nausea and vomiting 
  • Stomach Pain
  • Constipation
  • Dry Mouth
  • Increased thirst
  • Vaginal Itching

Helicobacter Pylori Test Price

The Helicobacter Pylori Test Price hovers around the average side and can be easily afforded. However, Helicobacter Pylori Test cost is not fixed across India and the Helicobacter Pylori Test cost can from one region to another.

Preparations Needed for Helicobacter Pylori (H. pylori) IgG antibodies Test

Preparatory instructions before the test *:

No Fasting Required.

No other special preparations required."

For the  breath test consult the doctor and avoid  certain medications

Understanding results of Helicobacter Pylori (H. pylori) IgG antibodies

Reference RangeInterpretation
"IgG 1.1 U/mL & Above IgA Below 8 U/mL **" "IgG Below 0.9 U/mL IgA 8 to 12 U/mL" "IgG 0.9 to 1.09 U/mL IgA Above 12 U/mL"Positive

Inference:
The presence of isotope labeled carbon dioxide indicates the presence of urease in the stomach. H . pylori produces urease which breaks down the labelled urea to produce labeled carbon-dioxide & ammonia.

‘*A Reference range is a set of values which helps the healthcare professional to interpret a medical test. It may vary with age, gender, and other factors. Reference ranges may also vary between labs, in value & units depending on instruments used and method of establishment of reference ranges’

References

  1. https://labtestsonline.org/tests/helicobacter-pylori-testing
  2. https://www.mayoclinic.org/diseases-conditions/h-pylori/diagnosis-treatment/drc-20356177
  3. https://medlineplus.gov/ency/article/007501.htm
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725530/
  5. https://kidshealth.org/en/parents/h-pylori.html
  6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047973/