Hemoglobin (Hb) Electrophoresis Lab Test

Thalassemia study, Sickle Cell Disease study
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Clinical Definition of Haemoglobin (Hb) Electrophoresis

Haemoglobin electrophoresis test helps detect various types of Haemoglobin in the blood. Haemoglobin is a substance in red blood cells that carries oxygen. It comes in many normal and abnormal forms. Haemoglobin electrophoresis uses the principle of gel electrophoresis to separate out various types of Haemoglobin. 

The most common type of Haemoglobin’s are:

Haemoglobin F: The normal type found in foetuses and newborns. It's replaced by Haemoglobin A soon after birth

Haemoglobin A: The normal type most commonly found in healthy kids and adults

Haemoglobin S, C, D, and E: are the abnormal Haemoglobin types

Production of too much of an abnormal type of Haemoglobin leads to blood disorders. Haemoglobin electrophoresis test detects the deficiency of normal Haemoglobin, abnormal levels of Haemoglobin S (Hbs) associated with sickle cell anaemia and abnormal Haemoglobin levels of Haemoglobin C associated with haemolytic anaemia.

What is Electrophoresis?

Electrophoresis simply put is a separation technique used in clinical and research laboratories for the purpose of separating molecules according to their size and electrical charge in a fluid or gel under the influence of an electric field.

Types of Electrophoresis:

The various types of electrophoresis are as follows;

  • Routine Electrophoresis
  • High Resolution Electrophoresis
  • Polyacrylamide gel Electrophoresis
  • Capillary Electrophoresis
  • Isoelectric Focussing
  • Immunochemical Electrophoresis
  • Two dimensional Electrophoresis
  • Pulse field Electrophoresis

When do you expect results?

24 to 36 Hours

Why Get Tested?

Haemoglobin electrophoresis analyses the various kinds of the oxygen-carrying protein (Haemoglobin) in the blood. This test is generally ordered to detect any diseases involving abnormal Haemoglobin production such as sickle cell diseases and thalassemia

Reason to take Haemoglobin (Hb) Electrophoresis Test

Symptoms associated and screened are:

  • Slowed growth and delayed puberty.
  • Bone problems
  • Poor appetite
  • Enlarged liver
  • Enlarged spleen
  • Dark urine
  • Jaundice (a yellowish color of the skin or whites of the eyes)
  • An enlarged Heart
  • Bone problems (especially bones in the face)
  • Shortness of breath
  • Dizziness
  • Headaches
  • Coldness in the hands and feet
  • Paler than normal skin or mucous membranes (the tissue that lines your nose, mouth, and other organs and body cavities)

Preparations Needed for Haemoglobin (Hb) Electrophoresis Test

Preparatory instructions before the test *:

No Fasting Required.

No other special preparations required.

Sample Required?

Specimen type: Serum

(Blood Sample) Specimen collection procedure: Venipuncture

(Collection of blood from a vein, usually from the arm)

Haemoglobin Electrophoresis Test Cost

The Haemoglobin Electrophoresis Test Cost is a tad expensive but, nothing too exorbitant. Moreover the Haemoglobin Electrophoresis Test Cost are quite variable and differ from one city to another.

How can we help?

Haemoglobin Electrophoresis lab test is a quite simple procedure, involving the collection of blood samples from a vein in the arms, and for such a basic procedure you don’t even need to step out of your house; our representative would visit you at your home and collect the required blood sample at the time and day of your convenience, and would also home deliver the Hb electrophoresis test results to you.

Our at – home healthcare services have won many rave reviews owing to our dedicated team of well experienced health professionals and patient centric approach. So just trust us for your Haemoglobin Electrophoresis Test and experience a high quality healthcare service delivered to you at your home.

Understanding results of Hemoglobin (Hb) Electrophoresis

Reference RangeInterpretation
Diseases/conditions related to the hemoglobin electrophoresis test Hemoglobin C disease Rare hemoglobinopathy Sickle cell anemia ThalassemiaMale

‘*A Reference range is a set of values which helps the healthcare professional to interpret a medical test. It may vary with age, gender, and other factors. Reference ranges may also vary between labs, in value & units depending on instruments used and method of establishment of reference ranges’.

References

  1. https://kidshealth.org/en/parents/test-electrophoresis.html
  2. https://labtestsonline.org/tests/hemoglobinopathy-evaluation
  3. https://www.allinahealth.org/CCS/doc/Thomson%20Consumer%20Lab%20Database/49/150016.htm