Antisperm Antibody Test Lab Test

Antisperm Antibody Test
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Clinical Definition of Antisperm Antibody Test

An antisperm antibody test looks for special proteins (antibodies) that fight against a man's sperm in blood, vaginal fluids, or semen. The test uses a sample of sperm and adds a substance that binds only to affected sperm.

Semen can cause an immune system response in either the man's or woman's body. The antibodies can damage or kill sperm. If a high number of sperm antibodies come into contact with a man's sperm, it may be hard for the sperm to fertilize an egg. The couple has a hard time becoming pregnant. This is also called immunologic infertility.

When do you expect results?

24 to 36 Hours

Why Get Tested?

The test diagnosis and analyzes the causes of infertility when a couple is unable to conceive; however it also analyzes the health of the reproductive organs. It is done as a blood test in females and as a sperm test in males. The antibodies can damage or destroy sperm causing infertility. This is called immuno-logical infertility. Anti sperm antibodies can be made in the body of the man in the following cases:

  • When the testicles are injuredAfter surgeries (such as a biopsy or vasectomy)
  • To check the success of a vasectomy ( sterilization procedure for males)
  • After a prostate gland infection
  • Testicular cancer 

A woman may have an allergic reaction to her partner’s semen, thus producing antibodies against it and causing infertility.

Reason to take Antisperm Antibody Test Test

Antisperm Antibody test is ordered when couples face fertility issues and the woman is unable to conceive.

Preparations Needed for Antisperm Antibody Test Test

Preparatory instructions before the test :
No special preparations required.

Sample Required?

Specimen type:For Women
Serum (Blood Sample)
Specimen collection procedure:
Venipuncture

Understanding results of Antisperm Antibody Test

Reference RangeInterpretation
00 to 60 U/ml **Normal
Above 60 U/mlElevated values

** Units per ml

‘*A Reference range is a set of values which helps the healthcare professional to interpret a medical test. It may vary with age, gender, and other factors. Reference ranges may also vary between labs, in value & units depending on instruments used and method of establishment of reference ranges’

References

  1. http://www.fertstert.org/article/S0015-0282(98)00302-1/fulltext
  2. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719312/
  3. http://www.nice.org.uk/donotdo/screening-for-antisperm-antibodies-should-not-be-offered-because-there-is-no-evidence-of-effective-treatment-to-improve-fertility
  4. http://www.uofmhealth.org/health-library/ux1248
  5. http://www.bioline.org.br/pdf?mf07004
  6. http://www.uofmhealth.org/health-library/ux1248