Anti Phospholipid Antibody (APA) -IgG / IgM Lab Test

Anti Phospholipid Antibody (APA) -IgG / IgM
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What Is Phospholipid?

Phospholipid is a type of lipid molecule with phosphate group that forms a major part of the cell membrane. Each Phospholipid constitutes of two fatty acids – one is the phosphate group and the other is the glycerol molecule. Phospholipid line themselves up in two parallel layers called Phospholipid bilayer and make up the cell membrane. Phospholipid is crucial to the cell’s ability to function.

How can we help?

We also offer APAS test as part of our highly reputable at-home healthcare service that too at an economical price. So, if you need APAS treatment at home just give us a call and connect with us as we have the resources and expertise to help you deal with the disease. 

Anti Phospholipid Antibody Syndrome symptoms

The common Antiphospholipid Antibody Syndrome symptoms are as follows;

  • Blood clots in the legs
  • Repeated miscarriages or still births
  • Stroke
  • Rash
  • Transitory Ischemic Attack

Few of the less common Antiphospholipid Antibody Syndrome symptoms are;

  • Persistent headaches
  • Migraines
  • Dementia
  • Seizure
  • Bleeding
  • Cardiovascular disease

Anti Phospholipid Antibody Syndrome Causes

The primary Antiphospholipid Antibody Syndrome cause includes underlying health conditions like an autoimmune disorder, infection and reaction to certain kind of medications.

Other risk factors to Antiphospholipid Antibody Syndrome are;

  • Infections like Syphilis, HIV/AIDS, Lyme disease
  • Lupus Erythematosus
  • Genetics 

Clinical Definition of Anti Phospholipid Antibody (APA) -IgG / IgM

Anti phospholipid antibodies (APA) are a group of autoantibodies that bind to negatively charged phospholipids. Anti phospholipid antibodies have been associated with thrombotic events which could lead to pregnancy loss, venous and arterial thrombosis and thrombocytopenia. Anti phospholipid antibodies prevent the blood to flow properly resulting in blood clots causing a health risk to both the mother and the baby. Some important types of phospholipid antibodies are: anticardiolipin; antinuclear and lupus antibodies.

When do you expect results?

24 to 36 Hours

Anti phospholipid Antibody Syndrome

Antiphospholipid Antibody Syndrome is an autoimmune disorder where the Antiphospholipid Antibodies attack the proteins that aid the binding of phospholipids to the plasma membrane. Antiphospholipid Antibody Syndrome are more common in young women than men. 

Reason to take Anti Phospholipid Antibody Test

Symptoms concerned with the antiphosolipid antibody are associated with shortness of breath, migraine headaches, deep vein thrombosis,stroke, heart attack, recurrent unexplained venous or arterial blood clots, recurrent unexplained thrombotic episodes, pain and swelling due to the thrombotic episodes, recurrent miscarriages, especially in the 2nd and 3rd trimesters, stillbirth, placental insufficiency, implantation failure, increased rates of IVF failure 

Preparations Needed for Anti Phospholipid Antibody (APA) -IgG / IgM Test

Preparatory instructions during specimen collection for antiphospholipid antibody test are*:

No Fasting Required.No other special preparations required.

Sample Required?

Specimen type:Serum (Blood Sample) Specimen collection procedure:Venipuncture - Collection of blood from a vein, usually from the arm.

Antiphospholipid Antibody Syndrome Treatment

The standard Antiphospholipid Antibody Syndrome treatment constitutes of medication that help the body in cutting down blood clots. For this blood thinning medication can be given. Other drugs can also be used to treat the conditions affecting the immune system. 

Antiphospholipid Antibody Syndrome Test cost

There is no fixed Antiphospholipid Antibody Syndrome test price as the Antiphospholipid Antibody Syndrome test cost is depended upon varied factors. Nevertheless, the Antiphospholipid Antibody Syndrome test cost are towards the average side and does not burn a hole in the patient’s pocket.

Why Get Tested?

The antiphospholipid antibody test detects increased levels of various antibodies. The process helps detect any particular set of specimens. It is an essential process in the body's ability to regulate the clotting of blood. antiphospholipid antibody test helps diagnose the reasons for recurrent miscarriage; asses or monitor a prolonged PTT (partial thromboplastin time) or assess the antiphospholipid antibody syndrome.

Understanding results of Anti Phospholipid Antibody (APA) -IgG / IgM

Reference RangeInterpretation
0.0 to 10.0 MPL Units/ml **Normal

‘*A Reference range is a set of values which helps the healthcare professional to interpret a medical test. It may vary with age, gender, and other factors. Reference ranges may also vary between labs, in value & units depending on instruments used and method of establishment of reference ranges’

References

  1. https://www.nhlbi.nih.gov/health-topics/antiphospholipid-antibody-syndrome
  2. https://resources.lupus.org/entry/testing-for-antiphospholipid-antibodies
  3. https://www.nhs.uk/conditions/antiphospholipid-syndrome/diagnosis/