clinical definition of homocysteine
Homocysteine is an amino acid C4H9NO2S found in animal metabolism and is usually a by-product of consuming meat. Increased amounts of homocysteine in the blood are associated with atherosclerosis, coronary heart disease, stroke, peripheral vascular disease and a possibility of Alzheimer's disease.
Homocysteine levels are greatly affected by diet (folic acid, vitamins B6 & B12) and by genetic factors. Studies found higher levels of vitamin B & folic Acid to have positive effects in partially lowering homocysteine levels in the blood.Foods high in folic acid are green, leafy vegetables and grain products; Vitamin B12 is Eggs and Milk and Vitamin B6 are peanuts, cashew nuts, potatoes and wheat products.
when do you expect results?
24 to 36 Hours
![](/static/5164cf588cc5299906cb7ca5d14fa681/9ccb6/Diagnostics.png)
why get tested?
This test ordered to diagnose a deficiency of Vitamin B6, B12, and folic acid or in a case of homocystinuria. It may also be carried out as a part of a lipid profile assessment or as a follow up to a heart attack or stroke.
reason to take homocysteine test
The common signs/symptoms are:
- Extreme tiredness and weakness
- Seizures
- Dislocation of the lens of the eye
- Abnormal bone structure
- Osteoporosis (weak bones)
- Blood clots
- Or decreased weight or rate of weight gain
- Slowed development in children
preparations needed for homocysteine test
Preparatory instructions before the test *:
- Fasting Required.
- Fasting samples have to be collected after a minimum 10-12 hour overnight fasting status.
- Clear fluids like water is allowed during this period. Refrain from consumption of early morning beverages like tea, coffee and milk until specimen collection is completed.
- In case of diabetics on oral or injectable hypoglycemic agents, consult your physician about continuing with these medications prior to specimen collection.
sample required?
Specimen type: Serum (Blood Sample)
Specimen collection procedure: Venipuncture (Collection of blood from a vein, usually from the arm)
Understanding results ofHomocysteine
Reference Range | Interpretation |
---|---|
4.44 - 13.56 µmol/L | Female |
5.46 - 16.2 µmol/L | male |
‘*A Reference range is a set of values which helps the healthcare professional to interpret a medical test. It may vary with age, gender, and other factors. Reference ranges may also vary between labs, in value & units depending on instruments used and method of establishment of reference ranges'