CA-125 (Cancer antigen-Ovary 125) Lab Test

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Clinical Definition of CA-125 (Cancer antigen-Ovary 125)

The cancer antigen 125 (CA-125) is a protein that exists on the top of ovarian cancer cells. It is developed by particular cells in the body including uterine tubes, uterus, cervix and the lining of the chest and abdominal cavities.

Eminent concentrations of CA-125 are observed in ovarian cancer and other non cancerous states like menstruation, pregnancy and pelvic inflammatory disease. The Cancer Antigen 125 (CA-125) test asseses the quantity of CA-125 in the blood.

When do you expect results?

24 to 36 Hours

Why Get Tested?

CA- 125 test is ordered to diagnose and monitor ovarian cancer treatment.

Reason to take CA-125 (Cancer antigen-Ovary 125) Test

Symptoms for ovarian cancer are Unusual vaginal bleeding (heavy periods, or bleeding after menopause)

Abdominal discomfort, pressure, bloating, or swelling, Loss of appetite, Indigestion, gas or nausea, pressure or pain in the abdomen, pelvis, back or legs.A swollen or bloated abdomen, indigestion, gas, constipation, or diarrhea; tiredness, Urinary Urgency and/or change in bowel habits and shortness of breath.

Preparations Needed for CA-125 (Cancer antigen-Ovary 125) Test

No Fasting Required.
No other special preparations required.

Sample Required?

Specimen type:Serum (Blood Sample)

Specimen collection procedure: Venipuncture (Collection of blood from a vein, usually from the arm)

Understanding results of CA-125 (Cancer antigen-Ovary 125)

Reference RangeInterpretation
0-30.2U/mlNormal

‘*A Reference range is a set of values which helps the healthcare professional to interpret a medical test. It may vary with age, gender, and other factors. Reference ranges may also vary between labs, in value & units depending on instruments used and method of establishment of reference ranges’

References

  1. https://www.mayoclinic.org/tests-procedures/ca-125-test/about/pac-20393295
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431838/
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872496/
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977011/